Multimerin-2 is a ligand for group 14 family C-type lectins CLEC14A, CD93 and CD248 spanning the endothelial pericyte interface
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چکیده
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the investigation of the relationship between type a and type b personalities and quality of translation
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The EMILIN/Multimerin Family
Elastin microfibrillar interface proteins (EMILINs) and Multimerins (EMILIN1, EMILIN2, Multimerin1, and Multimerin2) constitute a four member family that in addition to the shared C-terminus gC1q domain typical of the gC1q/TNF superfamily members contain a N-terminus unique cysteine-rich EMI domain. These glycoproteins are homotrimeric and assemble into high molecular weight multimers. They are...
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pericyte to myofibroblast transition and CKD. CD248 was first identified as a tumor vascular endothelial antigen in the early 1990s [8] ; however, it was later reported to be a marker of stromal fibroblasts and a subset of pericytes associated with tumor vessels as well as human mesenchymal stem cells, but not tumor endothelium [9, 10] . CD248 is known to bind to extracellular matrix proteins a...
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To recognise and respond to pathogens, germ-line encoded pattern recognition receptors (PRRs) bind to conserved microbial structures and activate host defence systems, including microbial uptake by phagocytosis. Phagocytosis is a complex process that is instrumental in the control of extracellular pathogens, and this activity is mediated by several PRRs, including a number of C-type lectins. Wh...
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Lectin of Wisteria floribunda specifically agglutinates group C streptococci. The reaction is strongly inhibited by N-acetyl-d-galactosamine, slightly by lactose, and not at all by galactose. The utility of the simple test of the lectin with group C streptococci is discussed.
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ژورنال
عنوان ژورنال: Oncogene
سال: 2017
ISSN: 0950-9232,1476-5594
DOI: 10.1038/onc.2017.214